A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response
Alkylating brokers harm DNA and proteins and are extensively utilized in most cancers chemotherapy. Whereas mobile responses to alkylation-induced DNA harm have been explored, information of how alkylation impacts world mobile stress responses is sparse. Right here, we examined the results of the alkylating agent methylmethane sulfonate (MMS) on gene expression in mouse liver, utilizing…
Read MoreA stepwise docking molecular dynamics approach for simulating antibody recognition with substantial conformational changes
Conformational modifications or rearrangements are frequent occasions throughout inter-biomolecular recognition. Monitoring these modifications are important for exploring the allosteric mechanism and it’s often achieved by molecular dynamics simulation in silico. We beforehand recognized a broad-neutralizing antibody towards H5 influenza virus, 13D4, and solved the crystal constructions of the free 13D4 Fab and its advanced with hemagglutinin…
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methylflash methylated dna quantification kit
Product Choices The MethylFlash™ Methylated DNA Quantification Bundle (Fluorometric) is a further refinement of our earlier SuperSense™ worldwide DNA methylation quantification kits by simplifying the workflow and enhancing the consistency of outcomes. It makes use of an progressive methodology to permit background alerts to be terribly low, eliminating the plate drying and blocking steps. Compared with chromatography-based methods…
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C ELISA Kits from MyBioSource
The ELISA (enzyme-linked immunosorbent assay) is a broadly used utility for detecting and quantifying proteins and antigens from varied samples. Goal-specific ELISA kits can be found from quite a lot of producers and may also help streamline your immunodetection experiments. Listed are ELISA Kits for the detection of cytochrome C, an alias title of cytochrome…
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pureexo exosome isolation kit
Software program Isolate pure exosome from cell custom media (supernatant). This bundle yields so much better purity than exosome precipitation methodology. This product is for evaluation use solely. Cat. No. BL-P100 PureExo Cell Producer 101Bio Key Choices Easy to utilize: No ultra-centrifugation (< 2 hours) 10 fold better yield (vs. completely different kits and…
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Concanavalin A Hepatitis plant lectin
Concanavalin A (Con A) is a plant lectin that is purified from jack beans. Con A binds to the mannose residues of varied glycoproteins and prompts lymphocytes. When Con A is run to mice, liver injury that can depend upon the activation of T lymphocytes by macrophages occurs (Tiegs et al., 1992). As a result of this reality, the model could allow the study of the pathophysiology…
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Arbor Assays | ELISA Kits, Detection Assays, & more
On January 1, 2017, Arbor Assays grew to develop into the world’s first Employee-Owned life sciences agency by way of a perpetual employee revenue perception (EBT). As an EBT, the board of directors ensures that the company stays an neutral entity for the benefit of prospects and employees. For the consumer, employee possession signifies that the…
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Mouse Anti-Nuclear Antigens
Alpha Diagnostic Worldwide Mouse Anti-Nuclear Antigens (ANA/ENA) Ig’s (whole (A+G+M) ELISA Package, 96 checks, Quantitative Producer: Alpha Diagnostic Worldwide This equipment measure ANA Ig’s (IgG+A+M) in mouse serum. It’s attainable to make use of isotype particular anti-mouse Ig, resembling anti-mouse IgM or anti-mouse IgG1-HRP, to measure isotype particular antibodies. Product Particulars Properties Assay kind Sandwich-ELISA Format…
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Galactose Binding-Soluble 3 ELISA Kit
Goose Lectin-Galactose Binding-Soluble three ELISA Equipment from MYBIOSOURCE INC. Product Identify Goose Lectin-Galactose Binding-Soluble three ELISA Equipment Description Assay Sort: Sandwich. Measurement n/a Focus n/a Purposes n/a Different Names [LGALS3; LGALS3 protein; galectin-3; lectin L-29; 35 kDa lectin; MAC-2 antigen; IgE-binding protein; laminin-binding protein; galactose-specific lectin 3; carbohydrate-binding protein 35; lectin, galactoside-binding, soluble, 3], [LGALS3;…
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Hemoglobin Test
Overview A hemoglobin take a look at measures the quantity of hemoglobin in your blood. Hemoglobin is a protein in your pink blood cells that carries oxygen to your physique’s organs and tissues and transports carbon dioxide out of your organs and tissues again to your lungs. If a hemoglobin take a look at reveals…
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