Concanavalin A Hepatitis plant lectin

• Jerry Martin

Concanavalin A (Con A) is a plant lectin that is purified from jack beans. Con A binds to the mannose residues of varied glycoproteins and prompts lymphocytes. When Con A is run to mice, liver injury that can depend upon the activation of T lymphocytes by macrophages occurs (Tiegs et al., 1992). As a result of this reality, the model could allow the study of the pathophysiology…