Tag: puc18/19
KRAS G12C-mutant non-small-cell lung cancer: biology, developmental therapeutics, and molecular testing
KRAS mutation is the most typical oncogenic driver in superior non-small cell lung most cancers (NSCLC), occurring in roughly 30% of lung adenocarcinomas. Over 80% of oncogenic KRAS mutations happen at codon 12 the place the glycine residue is substituted by totally different amino acids, resulting in genomic heterogeneity of KRAS-mutant tumors. The KRAS glycine-to-cysteine…
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Understanding the molecular evolution of tiger diversity through DNA barcoding marker ND4 and NADH dehydrogenase complex using computational biology
Background: At the moment, Tigers (the highest predator of an ecosystem) are on the checklist of endangered species. Thus the necessity is to grasp the tiger’s inhabitants genomics to design their conservation methods. Goal: We analyzed the molecular evolution of tiger variety utilizing NADH dehydrogenase subunit 4 (ND4), a major electron transport chain part. Strategies: We’ve got analyzed…
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