RNase R that converts 1 µg of poly(A)
APPLICATIONS:
• Enriching circRNAs in natural samples
• Identification of intronic lariat sequences
• Identification of exonic circRNAs
• Studying varied splicing
• Manufacturing of artificial spherical RNAs
DESCRIPTION:
RNase R is an E. coli exoribonuclease which shows 3’-to-5’ exonuclease train, successfully digesting virtually all linear RNA species. This enzyme does not digest spherical, lariat, or double stranded RNA with temporary 3’ overhangs (decrease than sevennucleotides). As such, this enzyme is ideally suited to the study of lariat RNA produced by typical splicing, along with circRNAs which come up by way of back-splicing.
EZYME UNIT DEFINITION: One unit is printed as the amount of RNase R that converts 1
µg of poly(A) into acid soluble nucleotides in 10 minutes at 37°C. ENZYME STORAGE BUFFER: 50 mM Tris-HCl (pH 7.5), 100mM NaCl, 0.1 mM EDTA, 1 mM DTT, and 50% (v/v) Glycerol 10X RNase R REACTION BUFFER COMPONENTS: 200 mM Tris-HCl, 1 M KCl, 1 mM, MgCl2, pH 7.5.
STORAGE CONDITIONS: Retailer at -20°C.
Stay away from repeated freeze-thaw cycles of all components to retain most effectivity. All components
are regular for one 12 months from the date of transport when saved and handled appropriately.
| Cat # +Dimension | M1228-500 |
|---|---|
| Dimension | 500 U |
| Highlights | RNase R is an E. coli exoribonuclease which shows 3’-to-5’ exonuclease train, successfully digesting virtually all linear RNA species. |
| Storage Conditions | -20°C |
| Supply Conditions | Gel Pack |
| USAGE | For Evaluation Use Solely! Not For Use in Individuals. |
RELATED PRODUCTS:
• RNase A (Cat# M1227-25)
• RNaseOFF ribonuclease Inhibitor (Cat# M1238-4000)
• DNase, E.coli DNA Ligase (Cat# M1217-100)
• Hyperlink-FAST 5 Minutes DNA Ligation Package deal (Cat# Okay902-50)
• New T4 DNA Ligase (Cat# M1247-200)
• T4 DNA Ligase (5 u/μl) (Cat# 9101-250)
• T4 RNA Ligase 1 (ssRNA Ligase) (Cat# M1218-100)
• T4 RNA Ligase 2 (dsRNA Ligase) (Cat# M1219-100)
 RNase FREE, 1 Liter Bottle Removes RNase & DNAse |
|||
| 10-173 | Genesee Scientific | 1 Bottle/Unit | EUR 337 |
 RNase FREE, 4 Liter Bottle Removes RNase & DNAse |
|||
| 10-456 | Genesee Scientific | 1 Bottle/Unit | EUR 403 |
 RNase FREE, 475ml Spray Bottle Removes RNase & DNAse |
|||
| 10-228 | Genesee Scientific | 1 Spray Bottle/Unit | EUR 300 |
 Rnase A, 1g |
|||
| R9001-1g | ACTGene | each | EUR 986.4 |
) RNase A (MBG) |
|||
| 409-050 | GeneOn | 50 mg | EUR 87.6 |
RNase A (MBG) |
|||
| 409-250 | GeneOn | 250 mg | EUR 231.6 |
 RNase III, E.coli |
|||
| M1226-100 | Biovision | each | EUR 268.8 |
 RNase L Antibody / Rnasel |
|||
| RQ6435 | NSJ Bioreagents | 100 ug | EUR 356.15 |
|
Description: RNase L is an enzyme that in humans is encoded by the RNASEL gene. This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. |
|||
 RNase L Peptide |
|||
| 46-735P | ProSci | 0.1 mg | EUR 405.6 |
|
Description: ABCE1 / RNase L Peptide |
|||
 RNase T2 Antibody |
|||
| abx237324-100ug | Abbexa | 100 ug | EUR 610.8 |
 RNase 1 Antibody |
|||
| 20-abx141499 | Abbexa |
|
|
 RNase 13 Antibody |
|||
| 20-abx141582 | Abbexa |
|
|
 RNAse H2A Peptide |
|||
| 4979P | ProSci | 0.05 mg | EUR 197.7 |
|
Description: (IN) RNAse H2A peptide |
|||
 RNase H1 Antibody |
|||
| DF12084 | Affbiotech | 200ul | EUR 420 |
 RNase A Solution |
|||
| G118 | ABM | 1.0 ml; 10 mg/ml | EUR 122.4 |
) DNase (RNase-free) |
|||
| abx098138-1500U | Abbexa | 1500 U | EUR 543.6 |
 RNase-Free water |
|||
| abx098145-25ml | Abbexa | 25 ml | EUR 210 |
 RNAse H2A Antibody |
|||
| 24819-100ul | SAB | 100ul | EUR 468 |
RNAse H2A Antibody |
|||
| 4979-002mg | ProSci | 0.02 mg | EUR 206.18 |
|
Description: RNAse H2A Antibody: Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids. The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair. RNAse H2 is made up of three subunits; all three are required for RNAse activity. Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid. Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system. |
|||
RNAse H2A Antibody |
|||
| 4979-01mg | ProSci | 0.1 mg | EUR 523.7 |
|
Description: RNAse H2A Antibody: Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids. The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair. RNAse H2 is made up of three subunits; all three are required for RNAse activity. Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid. Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system. |
|||
 Rnase A, Pancreatic |
|||
| abx082443-25mg | Abbexa | 25 mg | EUR 226.8 |
 Thermostable RNAse H |
|||
| M1224-100 | Biovision | each | EUR 385.2 |
 Murine Rnase inhibitor |
|||
| R301-01 | Vazyme | 2000 U | EUR 139.2 |
Murine Rnase inhibitor |
|||
| R301-02 | Vazyme | 10000 U | EUR 199.2 |
Murine Rnase inhibitor |
|||
| R301-03 | Vazyme | 20000 U | EUR 262.8 |
) RNase A (100 mg/ml) |
|||
| DE111-01 | Vazyme | 500 μl | EUR 23.2 |
 RNase H, 5u/ul |
|||
| BEN0202 | Bio Basic | 500U | EUR 199.2 |
 RiboSafe RNase Inhibitor |
|||
| BIO-65027 | Bioline | 2500 Units | Ask for price |
RiboSafe RNase Inhibitor |
|||
| BIO-65028 | Bioline | 10,000 Units | Ask for price |
 RNase I, 10u/ul |
|||
| BEN0601 | Bio Basic | 1KU | EUR 319.26 |
 DNASE I, RNASE FREE |
|||
| DD0649 | Bio Basic | 50KU | EUR 537.64 |
 Rat RNase ELISA Kit |
|||
| ERR0364 | Abclonal | 96Tests | EUR 625.2 |