Immunobiology and pathogenesis of hepatitis B virus infection
Hepatitis B virus (HBV) is a non-cytopathic, hepatotropic virus with the potential to trigger a persistent an infection, in the end resulting in cirrhosis and hepatocellular carcinoma.
Over the previous 4 many years, the fundamental ideas of HBV gene expression and replication in addition to the viral and host determinants governing an infection end result have been largely uncovered. Whereas HBV seems to induce little or no innate immune activation, the adaptive immune response mediates each viral clearance in addition to liver illness.
Right here, we assessment our present data on the immunobiology and pathogenesis of HBV an infection, focusing specifically on the position of CD8+ T cells and on a number of current breakthroughs that problem present dogmas.
For instance, we now belief that HBV integration into the host genome usually serves as a related supply of hepatitis B floor antigen (HBsAg) expression throughout continual an infection, presumably triggering dysfunctional T cell responses and favouring detrimental immunopathology.
Additional, the distinctive haemodynamics and anatomy of the liver – and the modifications they regularly endure throughout illness development to liver fibrosis and cirrhosis – profoundly affect T cell priming, differentiation and performance.
We additionally focus on why therapeutic approaches that restrict the intrahepatic inflammatory processes triggered by HBV-specific T cells is likely to be surprisingly useful for sufferers with continual an infection.
Schistosomes within the Lung: Immunobiology and Alternative
Schistosome an infection is a significant trigger of world morbidity, significantly in sub-Saharan Africa. Nonetheless, there is no such thing as a efficient vaccine for this main uncared for tropical illness, and re-infection routinely happens after chemotherapeutic therapy. Following invasion via the pores and skin, larval schistosomula enter the circulatory system and migrate via the lung earlier than maturing to maturity within the mesenteric or urogenital vasculature.
Eggs launched from grownup worms can turn into trapped in numerous tissues, with resultant inflammatory responses resulting in hepato-splenic, intestinal, or urogenital illness – processes which have been extensively studied lately.
In distinction, though lung pathology can happen in each the acute and continual phases of schistosomiasis, the mechanisms underlying pulmonary illness are significantly poorly understood. In continual an infection, egg-mediated fibrosis and vascular destruction can result in the formation of portosystemic shunts via which eggs can embolise to the lungs, the place they will set off granulomatous illness.
Acute schistosomiasis, or Katayama syndrome, which is primarily evident in non-endemic people, happens throughout pulmonary larval migration, maturation, and preliminary egg-production, usually involving fever and a cough with an accompanying immune cell infiltrate into the lung. Importantly, lung migrating larvae will not be only a reason behind irritation and pathology however are a key goal for future vaccine design.
Nonetheless, vaccine efforts are hindered by a restricted understanding of what constitutes a protecting immune response to larvae. On this assessment, we discover the present understanding of pulmonary immune responses and inflammatory pathology in schistosomiasis, highlighting necessary unanswered questions and areas for future analysis.
Immunobiology and nanotherapeutics of extreme acute respiratory syndrome 2 (SARS-CoV-2): a present replace
The emergence of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) constitutes essentially the most important international public well being problem in a century. It has reignited analysis curiosity in coronavirus.
- Whereas little data is out there, analysis is at the moment in progress to comprehensively perceive the final biology and immune response mechanism in opposition to SARS-CoV-2. The spike proteins (S protein) of SARS-CoV-2 carry out a vital operate in viral an infection institution. ACE2 and TMPRSS2 play a pivotal position in viral entry. “
- Upon viral entry, the launched pro-inflammatory proteins (cytokines and chemokines) trigger the migration of the T cells, monocytes, and macrophages to the an infection website.
- IFNϒ launched by T cells initiates a loop of pro-inflammatory suggestions. The inflammatory state might additional improve with a rise in immune dysfunction liable for the an infection’s development.
- A therapy strategy that stops ACE2-mediated viral entry and reduces inflammatory response is a vital therapeutic intervention technique, and nanomaterials and their conjugates are promising candidates. Nanoparticles can inhibit viral entry and replication.
- Nanomaterials have additionally discovered utility in focused drug supply and likewise in growing a vaccine in opposition to SARS-CoV-2. Right here, we briefly summarize the origin, transmission, and medical options of SARS-CoV-2. We then mentioned the immune response mechanisms of SARS-CoV-2.
- Lastly, we additional mentioned nanotechnology’s potentials as an intervention technique in opposition to SARS-CoV-2 an infection. All these understandings will likely be essential in growing therapeutic methods in opposition to SARS-CoV-2.
PD-1 immunobiology in glomerulonephritis and renal cell carcinoma
Background: Programmed cell demise protein (PD)-1 receptors and ligands on immune cells and kidney parenchymal cells assist preserve immunological homeostasis within the kidney. Dysregulated PD-1:PD-L1 binding interactions happen throughout the pathogenesis of glomerulopathies and renal cell carcinoma (RCC). The regulation of those molecules within the kidney is necessary to PD-1/PD-L1 immunotherapies that deal with RCC and should induce glomerulopathies as an opposed occasion.
Strategies: The expression and performance of PD-1 molecules on immune and kidney parenchymal cells had been reviewed within the wholesome kidney, PD-1 immunotherapy-induced nephrotoxicity, glomerulopathies and RCC.
Outcomes: PD-1 and/or its ligands are expressed on kidney macrophages, dendritic cells, lymphocytes, and renal proximal tubule epithelial cells. Vitamin D3, glutathione and AMP-activated protein kinase (AMPK) regulate hypoxic cell indicators concerned within the expression and performance of PD-1 molecules.
These pathways are altered in kidney illness and are linked to the manufacturing of vascular endothelial development issue, erythropoietin, adiponectin, interleukin (IL)-18, IL-23, and chemokines that bind CXCR3, CXCR4, and/or CXCR7.
These components are differentially produced in glomerulonephritis and RCC and could also be necessary biomarkers in sufferers that obtain PD-1 therapies and/or develop glomerulonephritis as an opposed occasion CONCLUSION: By evaluating the capabilities of the PD-1 axis in glomerulopathies and RCC, we recognized related chemokines concerned within the recruitment of immune cells and distinct mediators in T cell differentiation.
The expression and performance of PD-1 and PD-1 ligands in diseased tissue and significantly on double-negative T cells and parenchymal kidney cells wants continued exploration. The doable regulation of the PD-1 axis by vitamin D3, glutathione and/or AMPK cell indicators could also be necessary to kidney illness and the PD-1 immunotherapeutic response.
293AAV Cell Line |
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AAV-100 | Cell Biolabs | 1 vial | EUR 405 |
293RTV Cell Line |
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RV-100 | Cell Biolabs | 1 vial | EUR 405 |
293LTV Cell Line |
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LTV-100 | Cell Biolabs | 1 vial | EUR 405 |
293/GFP Cell Line |
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AKR-200 | Cell Biolabs | 1 vial | EUR 460 |
T47D/GFP Cell Line |
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AKR-208 | Cell Biolabs | 1 vial | EUR 686.4 |
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line. |
A549/GFP Cell Line |
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AKR-209 | Cell Biolabs | 1 vial | EUR 460 |
HeLa/GFP Cell Line |
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AKR-213 | Cell Biolabs | 1 vial | EUR 460 |
293/Cas9 Cell Line |
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AKR-5110 | Cell Biolabs | 1 vial | EUR 460 |
HeLa/Cas9 Cell Line |
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AKR-5111 | Cell Biolabs | 1 vial | EUR 460 |
NIH3T3/GFP Cell Line |
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AKR-214 | Cell Biolabs | 1 vial | EUR 460 |
NIH3T3/Cas9 Cell Line |
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AKR-5104 | Cell Biolabs | 1 vial | EUR 460 |
OVCAR-5/RFP Cell Line |
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AKR-254 | Cell Biolabs | 1 vial | EUR 686.4 |
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line. |
MCF-7-LUC cells |
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S0006002 | Addexbio | One Frozen vial | EUR 420 |
MCF7 [MCF-7] Cell Line |
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CL-0149 | Elabscience Biotech | 1×10⁶ cells/vial | EUR 420 |
Description: Homo sapiens, Human |
PKCa Stable Expressing MCF-7 (MCF-7/PKCa20) Cell Line |
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T6115 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Platinum-E Retroviral Packaging Cell Line, Ecotropic |
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RV-101 | Cell Biolabs | 1 vial | EUR 770 |
Platinum-GP Retroviral Packaging Cell Line, Pantropic |
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RV-103 | Cell Biolabs | 1 vial | EUR 770 |
Platinum-A Retroviral Packaging Cell Line, Amphotropic |
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RV-102 | Cell Biolabs | 1 vial | EUR 770 |
Total Protein - Murine Embryonic Stem Cell Line D3 |
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CBA-305 | Cell Biolabs | 500 ?g | EUR 414 |
Description:
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MCF 10A Cell Line |
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CL-0525 | Elabscience Biotech | 1×10⁶ cells/vial | EUR 500 |
Description: Homo sapiens, Human |
cDNA - Human Tumor Cell Line: MCF 7 |
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C1255830 | Biochain | 40 reactions | EUR 424 |
Flavopiridol-Resistant MCF-7 Cell Line (FLV100) |
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T8033 | ABM | 1x10^6 cells / 1.0 ml | EUR 2950 |
Flavopiridol-Resistant MCF-7 Cell Line (FLV1000) |
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T8035 | ABM | 1x10^6 cells / 1.0 ml | Ask for price |
AAV2-Luc Control Virus |
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AAV-320 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 2. |
AAV1-Luc Control Virus |
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AAV-321 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 1. |
AAV3-Luc Control Virus |
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AAV-323 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 3. |
AAV4-Luc Control Virus |
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AAV-324 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 4. |
AAV5-Luc Control Virus |
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AAV-325 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 5. |
AAV6-Luc Control Virus |
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AAV-326 | Cell Biolabs | 50 ?L | EUR 1221.6 |
Description: Luciferase control virus of AAV serotype 6. |
Total RNA - Human Tumor Cell Line: MCF 7 |
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R1255830-50 | Biochain | 50 ug | EUR 229 |
Genomic DNA - Human Tumor Cell Line: MCF 7 |
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D1255830 | Biochain | 100 ug | EUR 282 |
Total Protein - Human Tumor Cell Line: MCF 7 |
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P1255830 | Biochain | 1 mg | EUR 216 |
Luc-Akt-PH Stable MCF7 Cell Line |
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T3160 | ABM | 1x10^6 cells / 1.0 ml | EUR 3950 |
Membrane Protein - Human Tumor Cell Line: MCF 7 |
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P3255830 | Biochain | 0.1 mg | EUR 311 |
Paraffin Tissue Section - Human Tumor Cell Line: MCF-7 |
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T2255830 | Biochain | 5 slides | EUR 262 |
StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
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CBA-325 | Cell Biolabs | 96 assays | EUR 1027.2 |
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible) |
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CBA-325-5 | Cell Biolabs | 5 x 96 assays | EUR 4033.2 |
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis. |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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CBA-135 | Cell Biolabs | 96 assays | EUR 715 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric |
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CBA-135-5 | Cell Biolabs | 5 x 96 assays | EUR 3095 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
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CBA-140 | Cell Biolabs | 96 assays | EUR 750 |
CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric |
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CBA-140-5 | Cell Biolabs | 5 x 96 assays | EUR 3215 |
CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size |
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CBA-135-T | Cell Biolabs | 24 assays | EUR 518.4 |
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size |
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CBA-140-T | Cell Biolabs | 24 assays | EUR 547.2 |
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis. |
Collagen-based Cell Contraction Assay |
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CBA-201 | Cell Biolabs | 24 assays | EUR 420 |
Radius 384-Well Cell Migration Assay |
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CBA-127 | Cell Biolabs | 384 assays | EUR 721.2 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
Radius 384-Well Cell Migration Assay |
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CBA-127-5 | Cell Biolabs | 5 x 384 wells | EUR 2802 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
HIF-1 Alpha Cell Based ELISA Kit |
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CBA-281 | Cell Biolabs | 96 assays | EUR 734.4 |
Description: Cell Biolabs? HIF-1 Cell Based ELISA Kit is an immunoassay developed for rapid detection of HIF-1 Alpha in fixed cells. Cells on a microplate are stimulated for HIF-1 Alpha stabilization, fixed, permeabilized, and then neutralized in the well. HIF-1 Alpha is then detected with an anti-HIF-1 alpha antibody followed by an HRP conjugated secondary antibody. Each kit provides sufficient reagents to perform up to a total of 96 assays and can detect HIF-1 Alpha from human, mouse, or rat. |
CytoSelect™ MTT Cell Proliferation Assay |
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CBA-252 | Cell Biolabs | 960 assays | EUR 320 |
Radius™ 24-Well Cell Migration Assay |
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CBA-125 | Cell Biolabs | 24 assays | EUR 425 |
Radius™ 24-Well Cell Migration Assay |
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CBA-125-5 | Cell Biolabs | 5 x 24 assays | EUR 1820 |
Radius™ 96-Well Cell Migration Assay |
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CBA-126 | Cell Biolabs | 96 assays | EUR 495 |
Radius™ 96-Well Cell Migration Assay |
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CBA-126-5 | Cell Biolabs | 5 x 96 assays | EUR 2095 |
Radius™ 48-Well Cell Migration Assay |
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CBA-5037 | Cell Biolabs | 48 assays | EUR 445 |
Radius™ 48-Well Cell Migration Assay |
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CBA-5037-5 | Cell Biolabs | 5 x 48 assays | EUR 1895 |
CytoSelect™ BrdU Cell Proliferation ELISA Kit |
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CBA-251 | Cell Biolabs | 96 assays | EUR 455 |
CytoSelect Cell Proliferation Assay Reagent (Fluorometric) |
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CBA-250 | Cell Biolabs | 10 mL | EUR 490.8 |
Description: Cell Biolabs? CytoSelect Cell Proliferation Assay Reagent (Fluorometric) provides a fluorometric format for measuring and monitoring cell proliferation. Cells can be plated and then treated with compounds or agents that affect proliferation. Cells are then incubated with the proliferation reagent. Upon entering metabolically active live cells, the non-fluorescent proliferation reagent is converted into a bright red fluorescent form. An increase in cell proliferation is accompanied by increased fluorescent signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions. The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues. This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells. The kit contains sufficient reagents for the evaluation of 960 assays in ten 96-well plates or 192 assays in eight 24-well plates. |
CytoSelect™ 96-well Cell Transformation Assay |
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CBA-130 | Cell Biolabs | 96 assays | EUR 640 |
CytoSelect™ 96-well Cell Transformation Assay |
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CBA-130-5 | Cell Biolabs | 5 x 96 assays | EUR 2695 |
CytoSelect™ Cell Viability and Cytotoxicity Assay |
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CBA-240 | Cell Biolabs | 96 assays | EUR 305 |
CytoSelect™ 24-Well Cell Co-Culture System |
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CBA-160 | Cell Biolabs | 24 assays | EUR 365 |
CytoSelect™ 24-Well Cell Co-Culture System |
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CBA-160-5 | Cell Biolabs | 5 x 24 assays | EUR 1585 |
CytoSelect 24-well Laminin Cell Invasion, Colorimetric |
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CBA-110-LN | Cell Biolabs | 12 assays | EUR 714 |
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin. |
CytoSelect™ 48-Well Cell Contraction Assay Kit |
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CBA-5021 | Cell Biolabs | 48 assays | EUR 575 |
CytoSelect 384-well Cell Transformation Assay, Fluorometric |
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CBA-145 | Cell Biolabs | 384 assays | EUR 1208.4 |
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader. |
CytoSelect 384-well Cell Transformation Assay, Fluorometric |
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CBA-145-5 | Cell Biolabs | 5 x 384 assays | EUR 4681.2 |
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader. |
CytoSelect™ Cell Proliferation Assay Reagent (Colorimetric) |
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CBA-253 | Cell Biolabs | 10 mL | EUR 320 |
Radius 24-Well Cell Migration Assay, (Laminin Coated) |
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CBA-125-LN | Cell Biolabs | 24 assays | EUR 714 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
StemTAG PCR Primer Set for Stem Cell Characterization |
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CBA-303 | Cell Biolabs | 1 kit | EUR 470.4 |
Description: StemTAG PCR Primer Set for Stem Cell Characterization includes 7 primer pairs: Oct-4, NANOG, AFP, Flk-1, and NCAM, plus GAPDH and beta-actin as controls. |
MCF-7 Human breast cancer, noninvasive cell line: >1x10^10 frozen exosomes |
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EXOP-100A-1 | SBI | 50 ug | EUR 409 |
CytoSelect Clonogenic Tumor Cell Isolation Kit (5 preps) |
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CBA-155 | Cell Biolabs | 5 preps | EUR 957.6 |
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis. |
Radius 24-Well Cell Migration Assay, (Fibronectin Coated) |
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CBA-125-FN | Cell Biolabs | 24 assays | EUR 714 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
CytoSelect™ 24-well Collagen Cell Invasion, Colorimetric |
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CBA-110-COL | Cell Biolabs | 12 assays | EUR 535 |
Radius 24-Well Cell Migration Assay, (ECM Array Coated) |
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CBA-125-ECM | Cell Biolabs | 24 wells | EUR 838.8 |
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap. |
CytoSelect Proliferating Cell Nuclear Antigen (PCNA) ELISA Kit |
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CBA-254 | Cell Biolabs | 96 assays | EUR 672 |
Description: Cell Biolabs? CytoSelect Proliferating Cell Nuclear Antigen (PCNA) ELISA Kit is an enzyme immunoassay developed for the detection and quantitation of PCNA from nuclear and whole cell extracts. The kit detects PCNA from mouse, rat and human, and has a detection sensitivity limit of 12.5 ng/mLPCNA. Each kit provides sufficient reagents to perform up to 96 assays including standard curve and unknown samples. |
CytoSelect 48-well Cell Adhesion Assay (Laminin, Colorimetric) |
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CBA-056 | Cell Biolabs | 48 assays | EUR 512.4 |
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Laminin. |
CytoSelect 48-well Cell Adhesion Assay (Laminin, Fluorometric) |
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CBA-057 | Cell Biolabs | 48 assays | EUR 553.2 |
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Laminin. |
CytoSelect 24-well Laminin Cell Invasion Assay, Fluorometric |
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CBA-111-LN | Cell Biolabs | 12 assays | EUR 714 |
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin. |
CytoSelect 96-well Laminin Cell Invasion Assay, Fluorometric |
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CBA-112-LN | Cell Biolabs | 96 assays | EUR 908.4 |
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect 96-Well Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 96-well plates on a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin. |
CytoSelect 48-well Cell Adhesion Assay (Fibrinogen, Colorimetric) |
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CBA-058 | Cell Biolabs | 48 assays | EUR 512.4 |
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Fibrinogen. |
CytoSelect 48-well Cell Adhesion Assay (Fibrinogen, Fluorometric) |
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CBA-059 | Cell Biolabs | 48 assays | EUR 553.2 |
Description: Cell adhesion is a complex process involved in migration/invasion, embryogenesis, wound healing and tissue remodeling. Cells adhere to the extracellular matrix, forming complexes with cytoskeleton components that can affect cell motility, differentiation, proliferation, and survival. Our CytoSelect 48-Well Cell Adhesion Assays provide a fully quantitative method for the evaluation of cell adhesion. The 48-well plate is precoated with Fibrinogen. |
CytoSelect™ 96-well Phagocytosis Assay (Red Blood Cell) |
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CBA-220 | Cell Biolabs | 96 assays | EUR 540 |
Radius™ 24-Well Cell Migration Assay, (Collagen I Coated) |
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CBA-125-COL | Cell Biolabs | 24 assays | EUR 520 |
CytoSelect™ 24-well Collagen Cell Invasion Assay, Fluorometric |
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CBA-111-COL | Cell Biolabs | 12 assays | EUR 535 |
CytoSelect™ 96-well Collagen Cell Invasion Assay, Fluorometric |
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CBA-112-COL | Cell Biolabs | 96 assays | EUR 705 |
CytoSelect Clonogenic Tumor Cell Isolation Kit (5 x 5 preps) |
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CBA-155-5 | Cell Biolabs | 25 preps | EUR 3894 |
Description: Many solid tumors contain heterogeneous populations of normal and cancerous cells. Separation of these cell populations is key to an accurate assessment of the true genotypic and phenotypic differences between normal and tumor cells. Our CytoSelect Clonogenic Tumor Cell Isolation Kit uses a proprietary semisolid agar medium to facilitate formation of colonies by cells from solid tumors. Colonies are grown in either a 6-well plate or a 35mm culture dish. These colonies are isolated away from single (i.e. normal) cells by size filtration. The viable cells from these colonies can be easily recovered for further analysis. |
CytoSelect™ 48-well Cell Adhesion Assay (Fibronectin, Colorimetric) |
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CBA-050 | Cell Biolabs | 48 assays | EUR 370 |
CytoSelect™ 48-well Cell Adhesion Assay (Fibronectin, Fluorometric) |
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CBA-051 | Cell Biolabs | 48 assays | EUR 400 |
CytoSelect™ 24-well Cell Invasion (Basement Membrane), Fluorometric |
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CBA-111 | Cell Biolabs | 12 assays | EUR 535 |
CytoSelect™ 24-well Cell Migration Assay (8 μm), Colorimetric |
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CBA-100 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect™ 24-well Cell Migration Assay (8 μm), Colorimetric |
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CBA-100-5 | Cell Biolabs | 5 x 12 assays | EUR 2180 |
CytoSelect™ 24-well Cell Migration Assay (8 μm), Fluorometric |
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CBA-101 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect™ 24-well Cell Migration Assay (8 μm), Fluorometric |
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CBA-101-5 | Cell Biolabs | 5 x 12 assays | EUR 2180 |
CytoSelect™ 24-well Cell Migration Assay (5 μm), Fluorometric |
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CBA-102 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect™ 24-well Cell Migration Assay (5 μm), Fluorometric |
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CBA-102-5 | Cell Biolabs | 5 x 12 assays | EUR 2180 |
CytoSelect™ 24-well Cell Migration Assay (3 μm), Fluorometric |
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CBA-103 | Cell Biolabs | 12 assays | EUR 480 |
CytoSelect™ 24-well Cell Migration Assay (3 μm), Fluorometric |
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CBA-103-5 | Cell Biolabs | 5 x 12 assays | EUR 2180 |
CytoSelect™ 96-well Cell Migration Assay (3 μm), Fluorometric |
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CBA-104 | Cell Biolabs | 96 assays | EUR 580 |
CytoSelect™ 96-well Cell Migration Assay (3 μm), Fluorometric |
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CBA-104-5 | Cell Biolabs | 5 x 96 assays | EUR 2535 |
CytoSelect™ 96-well Cell Migration Assay (5 μm), Fluorometric |
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CBA-105 | Cell Biolabs | 96 assays | EUR 580 |