bioinfor

β-Defensins from common goby (Pomatoschistus microps) and silver trevally (Pseudocaranx georgianus): Molecular characterization and phylogenetic analysis

Antimicrobial peptides (AMPs) are biologically active molecules involved in host defense present in a variety of organisms. They are an integral component of innate immunity, forming a front line of defense against potential pathogens, including antibiotic-resistant ones. Fishes are proven to be a prospective source of AMPs as they are constantly being challenged by a…

Read More
bioinfor

MOLECULAR INVESTIGATION AND PHYLOGENETIC ANALYSIS OF ANAPLASMOSIS IN DOGS

  Anaplasmosis is a widespread vector-borne illness affecting canines, and Anaplasma platys is the key etiological agent of the illness. The research examines anaplasmosis molecular prevalence, associated threat elements, and alteration of hematological variables in Anaplasma-affected canines. A complete of 150 blood samples have been collected from canines within the district of Lahore, Pakistan. The…

Read More
bioinfor

First report of molecular and phylogenetic evaluation of Physaloptera praeputialis in naturally contaminated stray cats from India   Nematodes of the genus Physaloptera are globally distributed and infect a large number of hosts. Their life cycle includes orthopterans and coleopterans as intermediate hosts. The morphological characters alone are insufficient to detect and differentiate Physaloptera spp. from its congeners. Furthermore,…

Read More
bioinfor

Phylogenetic study of Theileria ovis and Theileria lestoquardi in sheep from Egypt: Molecular evidence and genetic characterization

Background and intention: Ovine theileriosis brought on by Theileria ovis and Theileria lestoquardi is a crucial infectious illness affecting small ruminants in areas of the tropic and subtropic zones. There may be restricted research about ovine theileriosis in Egypt; so the current research goals to evaluate the incidence of ovine theileriosis in Egypt on the molecular stage. <sturdy class=”sub-title”> Supplies…

Read More
bioinfor

An overview of molecular biology and nanotechnology based analytical methods for the detection of SARS-CoV-2: promising biotools for the rapid diagnosis of COVID-19

At present, the 2019 novel coronavirus (2019-nCoV) is drastically affecting 214 nations, inflicting extreme pneumonia in sufferers, which has resulted in lockdown being applied in a number of nations to cease its native transmission. Contemplating this, the fast screening and correct detection of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2; 2019-nCoV) play a vital position…

Read More
bioinfor

KRAS G12C-mutant non-small-cell lung cancer: biology, developmental therapeutics, and molecular testing

KRAS mutation is the most typical oncogenic driver in superior non-small cell lung most cancers (NSCLC), occurring in roughly 30% of lung adenocarcinomas. Over 80% of oncogenic KRAS mutations happen at codon 12 the place the glycine residue is substituted by totally different amino acids, resulting in genomic heterogeneity of KRAS-mutant tumors. The KRAS glycine-to-cysteine…

Read More
bioinfor

Understanding the molecular evolution of tiger diversity through DNA barcoding marker ND4 and NADH dehydrogenase complex using computational biology

Background: At the moment, Tigers (the highest predator of an ecosystem) are on the checklist of endangered species. Thus the necessity is to grasp the tiger’s inhabitants genomics to design their conservation methods. Goal: We analyzed the molecular evolution of tiger variety utilizing NADH dehydrogenase subunit 4 (ND4), a major electron transport chain part. Strategies: We’ve got analyzed…

Read More
bioinfor

Molecular Biology Methods in Streptomyces rimosus, a Producer of Oxytetracycline

Streptomyces rimosus is used for manufacturing of the broad-spectrum antibiotic oxytetracycline (OTC). S. rimosus belongs to Actinomyces species, a big group of microorganisms that produce various set of pure metabolites of excessive significance in lots of elements of our life. On this chapter, we describe particular molecular biology strategies and a classical homologous recombination strategy…

Read More
bioinfor

Entosis: From Cell Biology to Clinical Cancer Pathology

Entosis is a phenomenon, wherein one cell enters a second one. New clinico-histopathological research of entosis prompted us to summarize its significance in most cancers. It seems that entosis may be a novel, impartial prognostic predictor consider most cancers histopathology. We briefly focus on the organic foundation of entosis, adopted by a abstract of printed…

Read More
bioinfor

Molecular Biology of Basal and Squamous Cell Carcinomas

The prevalent keratinocyte-derived neoplasms of the pores and skin are basal cell carcinoma and squamous cell carcinoma. Each so-called non-melanoma pores and skin cancers comprise the most typical cancers in people by far. Widespread danger components for each tumor entities embrace solar publicity, DNA restore deficiencies resulting in chromosomal instability, or immunosuppression. But, basic variations…

Read More