Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells
Immune-based therapies similar to immune checkpoint inhibitors have revolutionized the systemic therapy of varied most cancers sorts. The therapeutic software of monoclonal antibodies focusing on inhibitory pathways similar to programmed cell death-1(PD-1)/programmed cell loss of life ligand 1 (PD-L1) and CTLA-Four to cells of the adaptive immune system has just lately been proven to generate significant enchancment within the medical final result of hepatocellular carcinoma (HCC).
However, present immunotherapeutic approaches induce sturdy responses in solely a subset of HCC sufferers. Since immunologic mechanisms similar to continual irritation on account of continual viral hepatitis or alcoholic and nonalcoholic fatty liver illness play an important position within the initiation, growth, and development of HCC, you will need to perceive the underlying mechanisms shaping the distinctive tumor microenvironment of liver most cancers.
The liver is an immunologic organ with massive populations of innate and innate-like immune cells and is uncovered to bacterial, viral, and fungal antigens by way of the gut-liver axis. Right here, we summarize and spotlight the position of those cells in liver most cancers and suggest methods to therapeutically goal them.
We additionally focus on present immunotherapeutic methods in HCC and description latest advances in our understanding of how the therapeutic potential of those brokers could be enhanced.
Peripheral blood T lymphocytosis in thymoma: an perception into immunobiology
Objective: Peripheral blood T lymphocytosis (PBTL) is a uncommon, but poorly understood manifestations of thymoma, which is postulated to be linked with autoimmune/paraneoplastic manifestations similar to myasthenia gravis (MG), pure crimson cell aplasia (PRCA), and so on.; extra generally encountered on this neoplasm.
Technique: We intention to explain the flowcytometric immunophenotypic information of PBTL in a 43-year-old male; 6 months after profitable completion of chemoradiotherapy (CT/RT) for a big, invasive, and metastatic kind B1 thymoma; and current a complete assessment of all such circumstances reported over final 42 years (N = 21) (1977-2019).
Consequence: A bigger dimension of the tumors (≥ 10 cm), presence of native invasion and/or distant metastasis, and sort B (cortical or lymphocyte wealthy) histology have been extra prone to be related to PBTL.
Tumors related to MG/PRCA (N = 9/21) are likely to have decrease PBTL in comparison with these with out such manifestations; and PBTL subsided following thymectomy with or with out CT/RT. Immunophenotypic evaluation of PB revealed a CD8 + > CD4 + mature (naïve) polyclonal T cells resembling late cortical thymocytes.
Conclusion: Thymic intratumoral microenvironment may affect incidence PBTL which will have a pathophysiologic hyperlink to the growth of autoimmune manifestations. Immunophenotypic traits of peripheral blood lymphoid cells ought to be the clue for correct characterization and to keep away from a misdiagnosis of a lymphoproliferative neoplasm.
Immunobiology of Acquired Resistance to Ticks
Ticks are blood-sucking arthropods of nice significance within the medical and veterinary fields worldwide. They’re thought of second solely to mosquitos as vectors of pathogenic microorganisms that may trigger severe infectious issues, such as Lyme borreliosis and tick-borne encephalitis.
Exhausting (Ixodid) ticks feed on host animals for a number of days and inject saliva along with pathogens to hosts throughout blood feeding. Some animal species can purchase resistance to blood-feeding by ticks after a single or repeated tick infestation, leading to decreased weights and numbers of engorged ticks or the loss of life of ticks in subsequent infestations. Importantly, this acquired tick resistance (ATR) can cut back the danger of pathogen transmission from pathogen-infected ticks to hosts.
That is the premise for the event of tick antigen-targeted vaccines to forestall tick infestation and tick-borne ailments. Accumulation of basophils is detected within the tick re-infested pores and skin lesion of animals exhibiting ATR, and the ablation of basophils abolishes ATR in mice and guinea pigs, illustrating the crucial position for basophils within the expression of ATR.
On this assessment article, we offer a complete overview of latest advances in our understanding of the mobile and molecular mechanisms accountable for the event and manifestation of ATR, with a selected deal with the position of basophils.
T-cell immunobiology and cytokine storm of COVID-19
2019 coronavirus illness (COVID-19) presents as a newly acknowledged pneumonia and will quickly progress into acute respiratory misery syndrome which has caused a world pandemic. Till now, no healing remedy has been strongly beneficial for COVID-19 aside from customized supportive care.
T cells and virus-specific T cells are important to guard in opposition to virus an infection, together with COVID-19. Delayed immune reconstitution (IR) and cytokine storm (CS) stay severe obstacles for the remedy of COVID-19.
Most COVID-19 sufferers, particularly amongst aged sufferers, had marked lymphopenia and elevated neutrophils, however T cell counts in extreme COVID-19 sufferers surviving the illness steadily restored later.
Elevated pro-inflammatory cytokines, significantly IL-6, IL-10, IL-2, and IL-17, and exhausted T cells are present in peripheral blood and the lungs. It means that Thymosin α1 and adoptive COVID-19-specific T cells might enhance IR whereas convalescent plasma, IL-6 blockade, mesenchymal stem cells, and corticosteroids might suppress CS.
Extra medical research on this discipline worldwide are urgently warranted to pave the best way for remedy of COVID-19 sooner or later.
In response to a necessity for a normal catalog of genome variation to deal with the large-scale sampling designs required by affiliation research, gene mapping and evolutionary biology, the Nationwide Middle for Biotechnology Data (NCBI) has established the dbSNP database [S.T.Sherry, M.Ward and K. Sirotkin (1999) Genome Res., 9, 677-679]. Submissions to dbSNP will probably be built-in with different sources of knowledge at NCBI similar to GenBank, PubMed, LocusLink and the Human Genome Venture information. The entire contents of dbSNP can be found to the general public at
Fluorescent proteins are genetically encoded, simply imaged reporters essential in biology and biotechnology. When a protein is tagged by fusion to a fluorescent protein, interactions between fluorescent proteins can undesirably disturb focusing on or operate. Sadly, all wild-type yellow-to-red fluorescent proteins reported to this point are obligately tetrameric and sometimes poisonous or disruptive.
The primary true monomer was mRFP1, derived from the Discosoma sp. fluorescent protein “DsRed” by directed evolution first to extend the pace of maturation, then to interrupt every subunit interface whereas restoring fluorescence, which cumulatively required 33 substitutions.
Though mRFP1 has already confirmed extensively helpful, a number of properties might bear enchancment and extra colours can be welcome. We report the following technology of monomers. The most recent crimson model matures extra utterly, is extra tolerant of N-terminal fusions and is over tenfold extra photostable than mRFP1. Three monomers with distinguishable hues from yellow-orange to red-orange have greater quantum efficiencies.
) PI in Fluorguard (0.5 µg/ml) |
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| F103 | Insitus Biotechnologies | 1 ml | EUR 86 |
) PI in Fluorguard (1 µg/ml) |
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| F104 | Insitus Biotechnologies | 1 ml | EUR 86 |
 PI |
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| PI | ImmunoStep | 400 test | EUR 154 |
 PI/RNAse |
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| PI/RNASE | ImmunoStep | 200 test | EUR 173.5 |
 50 ML AMPHOTERICIN B, LIQUID 250 µG/ML SOLUBILIZED |
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| 30-003-CF | CORNING | 50 mL/pk | EUR 81 |
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Description: Media Catalog; Cell Culture Reagents |
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 50 ML KANAMYCIN SULFATE, LIQUID, 5,000 µG/ML SOLUTION |
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| 30-006-CF | CORNING | 50 mL/pk | EUR 98 |
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Description: Media Catalog; Cell Culture Reagents |
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 Sol, 250 µg/mL) Amphotericin B (Fungizone) Sol, 250 µg/mL |
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| CCM1120-100 | Bio Basic | 100 mL | EUR 110.23 |
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 ELISA Kit) Human Proinsulin (PI) ELISA Kit |
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| DLR-PI-Hu-48T | DL Develop | 48T | EUR 479 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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Human Proinsulin (PI) ELISA Kit |
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| DLR-PI-Hu-96T | DL Develop | 96T | EUR 621 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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 ELISA Kit) Porcine Proinsulin (PI) ELISA Kit |
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| DLR-PI-p-48T | DL Develop | 48T | EUR 547 |
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Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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Porcine Proinsulin (PI) ELISA Kit |
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| DLR-PI-p-96T | DL Develop | 96T | EUR 715 |
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Description: A competitive inhibition quantitative ELISA assay kit for detection of Porcine Proinsulin (PI) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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Human Proinsulin (PI) ELISA Kit |
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| RDR-PI-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 500 |
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Human Proinsulin (PI) ELISA Kit |
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| RDR-PI-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 692 |
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Porcine Proinsulin (PI) ELISA Kit |
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| RDR-PI-p-48Tests | Reddot Biotech | 48 Tests | EUR 580 |
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Porcine Proinsulin (PI) ELISA Kit |
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| RDR-PI-p-96Tests | Reddot Biotech | 96 Tests | EUR 807 |
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Human Proinsulin (PI) ELISA Kit |
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| RD-PI-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 478 |
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Human Proinsulin (PI) ELISA Kit |
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| RD-PI-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 662 |
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Porcine Proinsulin (PI) ELISA Kit |
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| RD-PI-p-48Tests | Reddot Biotech | 48 Tests | EUR 555 |
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Porcine Proinsulin (PI) ELISA Kit |
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| RD-PI-p-96Tests | Reddot Biotech | 96 Tests | EUR 771 |
 10,000 µG/ML STREPTOMYCIN 25 µG/ML AMPHOTERICIN WITH 8.5 G/L NACI) 100 ML ANTIBIOTIC-ANTIMYCOTIC SOLUTION, 10,000 I.U. PENICILLIN (PER ML) 10,000 µG/ML STREPTOMYCIN 25 µG/ML AMPHOTERICIN WITH 8.5 G/L NACI |
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| 30-004-CI | CORNING | 100 mL/pk | EUR 103 |
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Description: Media Catalog; Cell Culture Reagents |
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 Latex-in-a-Box Conjugation Kit, Blue 0.3 micron, 7 mL |
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| LIB03-B007 | BioAssayWorks | 7 mL | EUR 733.94 |
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Description: Latex-in-a-Box Conjugation Kit conjugates blue 0.3 micron latex nanoparticles to antibodies and proteins. The nanoparticles are created using a special technology that needs only one hour to conjugate the particles to the antibody/protein. |
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 Latex-in-a-Box Conjugation Kit, Red 0.3 micron, 7 mL |
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| LIB03-R007 | BioAssayWorks | 7 mL | EUR 733.94 |
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Description: Latex-in-a-Box Conjugation Kit conjugates red 0.3 micron latex nanoparticles to antibodies and proteins. The nanoparticles are created using a special technology that needs only one hour to conjugate the particles to the antibody/protein. |
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 Fluorguard Antifade Mounting Medium |
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| F001 | Insitus Biotechnologies | 1 ml | EUR 86 |
 Penicillin-Streptomycin 100X Solution, 10, 000 Units/mL, 10, 000 µg/mL |
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| CCM1133-100 | Bio Basic | 100 mL | EUR 64.05 |
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 5,000 µG/ML STREPTOMYCIN) 100 ML PENICILLIN-STREPTOMYCIN SOLUTION, 50X, 5,000 I.U. PENICILLIN (PER ML) 5,000 µG/ML STREPTOMYCIN |
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| 30-001-CI | CORNING | 100 mL/pk | EUR 82 |
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Description: Media Catalog; Cell Culture Reagents |
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 10,000 µG/ML STREPTOMYCIN 29.2 MG/ML L-GLUTAMINE) 100 ML PENICILLIN-STREPTOMYCIN-L-GLUTAMINE, 100X, 10,000 I.U. PENCILLIN (PER ML) 10,000 µG/ML STREPTOMYCIN 29.2 MG/ML L-GLUTAMINE |
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| 30-009-CI | CORNING | 100 mL/pk | EUR 80 |
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Description: Media Catalog; Cell Culture Reagents |
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 Standards QQ and RR Phenotypes (2 x 0.3 mL)) Human Paraoxonase 1 (PON) Standards QQ and RR Phenotypes (2 x 0.3 mL) |
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| 0801384 | Zeptometrix | 2 x 0.3 mL | EUR 330.8 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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 pI |
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| EF007077 | Lifescience Market | 96 Tests | EUR 689 |
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PI |
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| abx290031-400tests | Abbexa | 400 tests | EUR 258 |
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 PI/ Rat PI ELISA Kit |
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| ELA-E0379r | Lifescience Market | 96 Tests | EUR 886 |
 0.3 ml 8-Strip Tubes & Domed Caps, 250 Strips of 8 Tubes and Caps |
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| GP209 | GenDepot | 2,000 tubes/caps | EUR 334 |
) Brilliant Cresyl Blue (0.3%, Alcoholic) |
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| BCA3800 | ScyTek Laboratories | 1 Gal. | EUR 241 |
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Brilliant Cresyl Blue (0.3%, Alcoholic) |
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| BCA500 | ScyTek Laboratories | 500 ml | EUR 90 |
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Brilliant Cresyl Blue (0.3%, Alcoholic) |
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| BCA999 | ScyTek Laboratories | 1000 ml | EUR 116 |
 Random Hexamers 100 µg |
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| 26-4000-03 | Gene Link | 100 ug | EUR 125 |
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Description: Random Primers are a mixture of oligonucleotides representing all possible sequence for that size. Random Primers can be used to prime synthesis in oligo-labeling similar to using hexamers (1,2) and cDNA synthesis. Random prime labeling yields high specific activity labeled DNA probe which can be used for all southern, northern and in situ hybridization studies. Random Primers can be also used similar to using hexamers in cDNA synthesis in combination with oligo d(T) to yield more 5' end cDNA sequence. Recently random primers have been used to detect DNA polymorphism. These polymorphisms, simply detected as DNA segments which amplify from one parent but not the other, are inherited in a Mendelian fashion and can be used to construct genetic maps in a variety of species. The authors suggested that these polymorphisms be called RAPD (pronounced RAPID) makers, after Random Amplified Polymorphic DNA (3). References 1. Feinberg, A.P. & Vogelstein, B. (1983) Anal. Biochem. 132:6-13. 2. Feinberg, A.P. & Vogelstein, B. (1984) Anal. Biochem. 137:266-267. 3. Williams J. G., Kubelik A.R., Livak K.J., Rafalski J.A. & Tingey S.V. (1990) Nucleic Acid Res. 18(22):6531-5. |
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 PI-103 |
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| 1728-1 | Biovision | EUR 153 | |
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PI-103 |
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| 1728-5 | Biovision | EUR 419 | |
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PI-103 |
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| 1728-50 | Biovision | Ask for price | |
 PI-3065 |
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| B1674-25 | Biovision | EUR 506 | |
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PI-3065 |
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| B1674-5 | Biovision | EUR 158 | |
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PI-3065 |
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| B4660-10 | ApexBio | 10 mg | EUR 224 |
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Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
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PI-3065 |
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| B4660-100 | ApexBio | 100 mg | EUR 792 |
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Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
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PI-3065 |
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| B4660-5 | ApexBio | 5 mg | EUR 166 |
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Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
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PI-3065 |
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| B4660-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 177 |
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Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
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PI-3065 |
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| B4660-50 | ApexBio | 50 mg | EUR 572 |
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Description: PI-3065 is a small molecule and selective inhibitor of p110?kinase with an Ki value of 1.5nM and IC50 value of 5nM [1].PI-3065 has been reported to selectively inhibit p110?kinase with Ki values of 15nM, 110nM, 130nM and 940nM |
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 PI-1840 |
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| B4755-10 | ApexBio | 10 mg | EUR 184 |
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Description: PI-1840 is a potent and selective inhibitor of proteasome with IC50 value of 27 nM for chymotrypsinlike (CT-L) activity [1]. The 26S proteasome consists of a 19S regulatory particle (RP) and a 20S core particle. |
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PI-1840 |
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| B4755-50 | ApexBio | 50 mg | EUR 522 |
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Description: PI-1840 is a potent and selective inhibitor of proteasome with IC50 value of 27 nM for chymotrypsinlike (CT-L) activity [1]. The 26S proteasome consists of a 19S regulatory particle (RP) and a 20S core particle. |
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PI-103 |
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| E1KS1038 | EnoGene | 5mg | EUR 325 |
 PI 828 |
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| B7198-1 | ApexBio | 1 mg | EUR 126 |
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PI 828 |
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| B7198-10 | ApexBio | 10 mg | EUR 318 |
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PI 828 |
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| B7198-5 | ApexBio | 5 mg | EUR 203 |
 PI / RNAse |
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| abx290029-200tests | Abbexa | 200 tests | EUR 272 |
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PI-103 |
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| A2067-25 | ApexBio | 25 mg | EUR 328 |
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Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
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PI-103 |
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| A2067-5 | ApexBio | 5 mg | EUR 147 |
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Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
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PI-103 |
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| A2067-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 154 |
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Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
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PI-103 |
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| A2067-S | ApexBio | Evaluation Sample | EUR 81 |
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Description: PI-103 is a potent and selective inhibitor of class I PI3K, mTOR and DNA-PK with IC50 values of 2, 3, 3, 15, 30 and 23 nM for p110?, p110?, p110?, p110?, mTOR and DNA-PK, respectively [1]. |
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PI-3065 |
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| HY-12235 | MedChemExpress | 10mM/1mL | EUR 204 |
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PI-1840 |
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| HY-12286 | MedChemExpress | 50mg | EUR 587 |
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PI-103 |
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| HY-10115 | MedChemExpress | 100mg | EUR 546 |
 PI-828 |
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| HY-108606 | MedChemExpress | 1mg | EUR 142 |
 BrightGreen miRNA qPCR MasterMix-Low ROX |
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| MasterMix-mL | ABM | 4 x 1.25 ml for 500 reactions | EUR 151 |
 (rat IgG2b)) Rat Monoclonal Anti-Mouse CD4 Pur. Low Endotoxin (Clone YTS 191.1) (rat IgG2b) |
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| MCD004-ML | Alpha Diagnostics | 100 ug | EUR 408 |
 (rat IgG1)) Rat Monoclonal Anti-Mouse CD25 , Pur. Low Endotoxin (Clone PC61.5.3) (rat IgG1) |
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| MCD025-ML | Alpha Diagnostics | 100 ug | EUR 408 |
 Antibody) Glutathione S-Transferase Pi (GST pi) Antibody |
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| abx020559-10ug | Abbexa | 10 ug | EUR 342 |
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 DiagPoly Amine Polystyrene Particles, 0.3 µm |
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| DNM-F002 | Creative Diagnostics | 10 mL | EUR 580 |
 PI-8 antibody |
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| 70R-12052 | Fitzgerald | 100 ug | EUR 392 |
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Description: Rabbit polyclonal PI-8 antibody |
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 PI-8 Antibody |
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| 3748-100 | Biovision | EUR 316 | |
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PI-8 Antibody |
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| 3748-30T | Biovision | EUR 146 | |
 Antibody) Phosphatidylinositol (PI) Antibody |
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| 20-abx179006 | Abbexa |
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 PI Staining Kit |
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| abx097208-1Kit | Abbexa | 1 Kit | EUR 230 |
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 Human PI Protein |
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| 20-abx650990 | Abbexa |
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 PI-103 Hydrochloride |
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| A3724-100 | ApexBio | 100 mg | EUR 838 |
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Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
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PI-103 Hydrochloride |
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| A3724-25 | ApexBio | 25 mg | EUR 328 |
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Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
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PI-103 Hydrochloride |
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| A3724-5 | ApexBio | 5 mg | EUR 147 |
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Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
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PI-103 Hydrochloride |
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| A3724-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 154 |
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Description: PI-103 is a dual inhibitor of PI3K/Akt and mTOR with IC50 value of 0.002 ?M , 0.003?M, 0.003?M, 0.015?M, 0.030?M for P110?, P110?, P110?, P110 and mTOR, respectively. |
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 Pi-Methylimidazoleacetic acid |
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| HY-113274 | MedChemExpress | 5mg | EUR 187 |
) PI-103 (Hydrochloride) |
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| HY-10115A | MedChemExpress | 5mg | EUR 119 |
) Recombinant Proinsulin (PI) |
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| 4-RPA379Hu01 | Cloud-Clone |
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Description: Recombinant Human Proinsulin expressed in: E.coli |
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 DAPI, 10mg/mL in H2O |
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| 40043 | Biotium | 1ML | EUR 134 |
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Description: Minimum order quantity: 1 unit of 1ML |
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 DiagPoly Plain Polystyrene Particles, 0.2-0.3 µm |
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| DNM-P003 | Creative Diagnostics | 10 mL | EUR 554 |
 Anti-Pichia pastoris HCP |
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| PI-49 | Cygnus Technologies | 1 ml | EUR 334 |
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Description: Anti-Pichia pastoris HCP by Cygnus Technologies is available in Europe via Gentaur. |
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Anti-Pichia pastoris HCP |
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| PI-49AF | Cygnus Technologies | 1 mg | EUR 1913 |
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Description: Anti-Pichia pastoris HCP by Cygnus Technologies is available in Europe via Gentaur. |
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Anti-Pichia pastoris HCP |
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| PI-49PA | Cygnus Technologies | 1 ml | EUR 488 |
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Description: Anti-Pichia pastoris HCP by Cygnus Technologies is available in Europe via Gentaur. |
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 antiserum) Rabbit Anti-Rat Glutathione Transferees pi (GST-pi) antiserum |
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| GSTP11-S | Alpha Diagnostics | 100 ul | EUR 457 |
 antiserum) Rabbit Anti-Human Glutathione Transferase Pi (GST-pi) antiserum |
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| GSTP12-S | Alpha Diagnostics | 100 ul | EUR 457 |
) Anti-PON1 Clone KRJ1 (100 µg) |
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| 0801012 | Zeptometrix | 100 µg | EUR 284 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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) Anti-PON1 Clone KRJ2 (100 µg) |
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| 0801014 | Zeptometrix | 100 µg | EUR 284 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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 bFGF-nAb Purified Protein 25 µg |
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| ABP-NAB-BFGFAB | Allele Biotech | 25 µg | Ask for price |
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 bFGF-nAb Plus Biotinylated 25 µg |
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| ABP-NAB-BFGFPB | Allele Biotech | 25 µg | Ask for price |
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 GFP-nAb Purified Protein 25 µg |
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| ABP-NAB-GFPAB | Allele Biotech | 25 µg | Ask for price |
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 GFP-nAb Plus Biotinylated 25 µg |
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| ABP-NAB-GFPPB | Allele Biotech | 25 µg | Ask for price |
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 mNeonGreen-nAb Purified Protein 25 µg |
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| ABP-NAB-MNGAB | Allele Biotech | 25 µg | Ask for price |
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 mNeonGreen-nAb Plus Biotinylated 25 µg |
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| ABP-NAB-MNGPB | Allele Biotech | 25 µg | Ask for price |
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 RFP-nAb Purified Protein 25 µg |
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| ABP-NAB-RFPAB | Allele Biotech | 25 ug | Ask for price |
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 RFP-nAb Plus Biotinylated 25 µg |
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| ABP-NAB-RFPPB | Allele Biotech | 25 µg | Ask for price |
|
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 PI-8 Blocking Peptide |
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| 33R-10913 | Fitzgerald | 50 ug | EUR 191 |
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Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PI-8 antibody, catalog no. 70R-12052 |
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PI-8 Blocking Peptide |
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| 3748BP-50 | Biovision | EUR 153 | |
 PI-9 Polyclonal Antibody |
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| 41341-100ul | SAB | 100ul | EUR 252 |
